Working in the same position for long periods of time at a computer puts your muscles under constant strain, reducing blood flow and oxygen to hard-working tissues. It helps to take a break by alternating the types of tasks you perform throughout the day.
Here are some breaks to consider:
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Eye Breaks: Every 15 minutes you should briefly look away from the screen for a minute or two shifting your line of sight to a more distant scene.
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Micro-Breaks: During a micro-break (< 2minutes) stretch, stand up, move around, or do a different work task e.g. such as making a phone call, filing, or any other work that does not involve keyboarding and mousing.
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Rest Breaks: Every 30 to 60 minutes you should take a brief break. Here again, this could be as simple as performing a task that does not involve computing.